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Article

IL-1β gene polymorphism and serum levels in a Tunisian population with acute heart failure.

Biomarkers in medicine - 1 Dec 2017

Imen Trabelsi, Salma Messous, Khouloud Chehaibi, Habib Grissa Mohammed, Kaouthar Beltaief, Nejia Tounsi, Imen Gannoun, Hamdi Boubaker, Riadh Boukef, Wahid Bouida, Naceur Slimane Mohamed, Semir Nouira

Abstract excerpt

AIM: The aim of this study was to explore the relationship between IL-1β-31T/C polymorphism and serum levels of IL-1β and the risk of acute heart failure (AHF). METHODS: A total of 320 dyspnea patients (160 with AHF and 160 without AHF) and 100 healthy subjects were included in this study. IL-1β genotyping was performed by PCR-restriction fragment length polymorphism technique. RESULTS: Concentration of IL-1β was...

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PMID: 29182005
DOI: 10.2217/bmm-2017-0179

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