Article
Association between genetic variations of NMDA receptor NR3 subfamily genes and heroin addiction in male Han Chinese.
Neuroscience letters - 19 Sept 2016
Xie Xiaohu, Liu Huifen, Zhang Jianbing, Chen Weisheng, Zhuang Dingding, Duan Shiwei, Zhou Wenhua
Abstract excerpt
Growing amounts of evidence suggest that N-Methyl-d-aspartate (NMDA) receptor mediated glutamate neurotransmission may be involved in the pathophysiology of drug dependence. The NMDA receptor consists of three subfamilies (NR1, NR2, and NR3). The ability of subunit NR3 to negatively modulate the NMDA receptor function makes it an attractive candidate gene of heroin addiction. The purpose of this study is to...
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