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Article

PEBP1, a RAF kinase inhibitory protein, negatively regulates starvation-induced autophagy by direct interaction with LC3.

Autophagy - 1 Nov 2016

Noh Hae Sook, Hah Young-Sool, Zada Sahib, Ha Ji Hye, Sim Gyujin, Hwang Jin Seok, Lai Trang Huyen, Nguyen Huynh Quoc, Park Jae-Yong, Kim Hyun Joon, Byun June-Ho, Hahm Jong Ryeal, Kang Kee Ryeon, Kim Deok Ryong

Abstract excerpt

Autophagy plays a critical role in maintaining cell homeostasis in response to various stressors through protein conjugation and activation of lysosome-dependent degradation. MAP1LC3B/LC3B (microtubule- associated protein 1 light chain 3 β) is conjugated with phosphatidylethanolamine (PE) in the membranes and regulates initiation of autophagy through interaction with many autophagy-related proteins possessing an...

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Identifiers

PMID: 27540684
DOI: 10.1080/15548627.2016.1219013
PMCID: PMC5103343

Genes

PEBP1
ULK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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