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Article

Systematic analysis of ATG13 domain requirements for autophagy induction.

Autophagy - 1 Jan 2018

Wallot-Hieke Nora, Verma Neha, Schlütermann David, Berleth Niklas, Deitersen Jana, Böhler Philip, Stuhldreier Fabian, Wu Wenxian, Seggewiß Sabine, Peter Christoph, Gohlke Holger, Mizushima Noboru, Stork Björn

Abstract excerpt

Macroautophagy/autophagy is an evolutionarily conserved cellular process whose induction is regulated by the ULK1 protein kinase complex. The subunit ATG13 functions as an adaptor protein by recruiting ULK1, RB1CC1 and ATG101 to a core ULK1 complex. Furthermore, ATG13 directly binds both phospholipids and members of the Atg8 family. The central involvement of ATG13 in complex formation makes it an attractive...

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Source

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Identifiers

PMID: 29173006
DOI: 10.1080/15548627.2017.1387342
PMCID: PMC6070014

Genes

ATG13
ULK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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