Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The hedgehog pathway in triple‐negative breast cancer

18 Aug 2016

Abstract excerpt

Treatment of triple-negative breast cancer (TNBC) remains challenging due to the underlying heterogeneity of this disease coupled with the lack of predictive biomarkers and effective targeted therapies. Intratumoral heterogeneity, particularly enrichment for breast cancer stem cell-like subpopulations, has emerged as a leading hypothesis for systemic therapy resistance and clinically aggressive course of poor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Hedgehog Signaling Pathway Studies
Share to Tumors and Oncological Cases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27539549
DOI: 10.1002/cam4.833

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The hedgehog pathway in triple‐negative breast cancerPMID 27539549Read ↗

Role of Hedgehog Signaling in Breast Cancer: Pathogenesis and TherapeuticsSemantic proximity Read ↗

An Insight Into the Cancer Stem Cell Survival Pathways Involved in Chemoresistance in Triple-Negative Breast CancerSemantic proximity Read ↗

Targeting Cellular Signaling Pathways in Breast Cancer Stem Cells and its Implication for Cancer Treatment.Semantic proximity Read ↗

Breast Cancer Stem Cells and Tumor Heterogeneity: Characteristics and Therapeutic StrategiesSemantic proximity Read ↗

Translational drugs targeting cancer stem cells in triple-negative breast cancerSemantic proximity Read ↗

Signaling pathways governing the maintenance of breast cancer stem cells and their therapeutic implicationsSemantic proximity Read ↗

Signaling pathways essential for triple-negative breast cancer stem-like cellsSemantic proximity Read ↗

An update on cancer stem cell survival pathways involved in chemoresistance in triple-negative breast cancerSemantic proximity Read ↗

Breast Cancer Stem CellsSemantic proximity Read ↗

Hedgehog Pathway Is a Regulator of Stemness in HER2-Positive Trastuzumab-Resistant Breast CancerSemantic proximity Read ↗

Targeting stromal remodeling and cancer stem cell plasticity to overcome chemoresistance in triple negative breast cancerSemantic proximity Read ↗

Targeting the Key Signaling Pathways in Breast Cancer: From Molecular Mechanism to Therapeutic InterventionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.