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Article

The effect of colesevelam treatment on bile acid and lipid metabolism and glycemic control in healthy men.

Physiological research - 13 Dec 2016

Blahová T, Peterková L, Leníček M, Vlachová M, Zemánková K, Adámková V, Vítek L, Kovář J

Abstract excerpt

The treatment of hypercholesterolemia with bile acid (BA) sequestrants results in upregulation of BA synthesis through the classical pathway initiated by cholesterol 7alpha-hydroxylase (CYP7A1). To characterize the detailed dynamics of serum lipid and BA concentrations and the BA synthesis rate in response to treatment with BA sequestrants and to determine whether the -203A/C promoter polymorphism of the CYP7A1...

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Source

Identifiers

PMID: 27539104
DOI: 10.33549/physiolres.933276

Genes

FGF19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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