Article
Familial idiopathic normal pressure hydrocephalus.
Journal of the neurological sciences - 15 Sept 2016
Huovinen Joel, Kastinen Sami, Komulainen Simo, Oinas Minna, Avellan Cecilia, Frantzen Janek, Rinne Jaakko, Ronkainen Antti, Kauppinen Mikko, Lönnrot Kimmo, Perola Markus, Pyykkö Okko T, Koivisto Anne M, Remes Anne M, Soininen Hilkka, Hiltunen Mikko, Helisalmi Seppo, Kurki Mitja, Jääskeläinen Juha E, Leinonen Ville
Abstract excerpt
Idiopathic normal pressure hydrocephalus (iNPH) is a late-onset surgically alleviated, progressive disease. We characterize a potential familial subgroup of iNPH in a nation-wide Finnish cohort of 375 shunt-operated iNPH-patients. The patients were questionnaired and phone-interviewed, whether they have relatives with either diagnosed iNPH or disease-related symptomatology. Then pedigrees of all families with...
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