Risk Variants Associated With Normal Pressure Hydrocephalus: Genome-Wide Association Study in the FinnGen Cohort.

doi:10.1212/WNL.0000000000209694

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Risk Variants Associated With Normal Pressure Hydrocephalus: Genome-Wide Association Study in the FinnGen Cohort.

Neurology - 10 Sept 2024

Räsänen Joel, Heikkinen Sami, Mäklin Kiira, Lipponen Anssi, Kuulasmaa Teemu, Mehtonen Juha, Korhonen Ville E, Junkkari Antti, Grenier-Boley Benjamin, Bellenguez Celine, Oinas Minna, Avellan Cecilia, Frantzén Janek, Kotkansalo Anna, Rinne Jaakko, Ronkainen Antti, Kauppinen Mikko, von Und Zu Fraunberg Mikael, Lönnrot Kimmo, Satopää Jarno, Perola Markus, Koivisto Anne M, Julkunen Valtteri, Portaankorva Anne M, Mannermaa Arto, Soininen Hilkka, Helisalmi Seppo, Jääskeläinen Juha E, Lambert Jean-Charles, Eide Per K, Palotie Aarno, Kurki Mitja I, Hiltunen Mikko, Leinonen Ville

Abstract excerpt

BACKGROUND AND OBJECTIVES: Large-scale genome-wide studies of chronic hydrocephalus have been lacking. We conducted a genome-wide association study (GWAS) in normal pressure hydrocephalus (NPH). METHODS: We used a case-control study design implementing FinnGen data containing 473,691 Finns with genotypes and nationwide health records. Patients with NPH were selected based on ICD-10 G91.2 diagnosis. To select...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to Case-Control Studies

Share to Cohort Studies

Share to Finland

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 39141892
DOI: 10.1212/WNL.0000000000209694
PMCID: PMC11361830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Risk Variants Associated With Normal Pressure Hydrocephalus: Genome-Wide Association Study in the FinnGen Cohort.PMID 39141892Read ↗

Multi-omic analysis elucidates the genetic basis of hydrocephalusSemantic proximity Read ↗

Genetics of idiopathic intracranial hypertension (IIH): Integration of population studies and clinical dataSemantic proximity Read ↗

Relationship between plasma proteome and hydrocephalus: a two-sample Mendelian randomization analysisSemantic proximity Read ↗

CWH43 Variants Are Associated With Disease Risk and Clinical Phenotypic Measures in Patients With Normal Pressure HydrocephalusSemantic proximity Read ↗

The genetics of idiopathic intracranial hypertension (IIH): Integration of population studies and clinical dataSemantic proximity Read ↗

Congenital hydrocephalus: new Mendelian mutations and evidence for oligogenic inheritance.Semantic proximity Read ↗

Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus.Semantic proximity Read ↗

The genetic basis of hydrocephalus: genes, pathways, mechanisms, and global impactSemantic proximity Read ↗

Alzheimer's Disease-Related Polymorphisms in Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus.Semantic proximity Read ↗

The genetic background of hydrocephalus in a population-based cohort: implication of ciliary involvementSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.