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[ALLELE POLYMORPHISM OF THE IFNG AND TGFB GENES AS A FACTOR OF MODULATION OF CYTOKINE SECRETION AND SUSCEPTIBILITY TO PULMONARY TUBERCULOSIS].

Tuberkulez i bolezni legkikh - 1 Jan 2010

Abstract excerpt

By applying the current immunological and molecular genetic studies, the authors revealed a genetically determined imbalance in the pro- duction of immunoregulatory cytokines by monoluclear leukocytes in pulmonary tuberculosis. T allele and TT genotype of IFNG gene poly- morphism +874A/T were found to be an immunogenetic factor that had a protective effect against susceptibility to pulmonary tuberculosis....

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Share to Cytokines
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27534050

Genes

IFNG

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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[ALLELE POLYMORPHISM OF THE IFNG AND TGFB GENES AS A FACTOR OF MODULATION OF CYTOKINE SECRETION AND SUSCEPTIBILITY TO PULMONARY TUBERCULOSIS].PMID 27534050Read ↗

IFNG +874T/A polymorphism and cytokine plasma levels are associated with susceptibility to Mycobacterium tuberculosis infection and clinical manifestation of tuberculosis.Semantic proximity Read ↗

Allelic polymorphism of cytokine genes during pulmonary tuberculosis.Semantic proximity Read ↗

[Determination of the cytokine gene polymorphism and genetic susceptibility in tuberculosis patients].Semantic proximity Read ↗

Association of Cytokine Gene Polymorphisms and Their Impact on Active and Latent Tuberculosis in Brazil's Amazon Region.Semantic proximity Read ↗

Association of polymorphism +874 A/T of interferon-γ and susceptibility to the development of tuberculosis: meta-analysis.Semantic proximity Read ↗

[Association between polymorphisms of interleukin-10, interferon-γ gene and the susceptibility to pulmonary tuberculosis].Semantic proximity Read ↗

Association between cytokine gene polymorphisms and tuberculosis in a Chinese population in Shanghai: a case-control study.Semantic proximity Read ↗

Interferon-γ (+874 T/A) and interleukin-10 (-1082 G/A) genes polymorphisms are associated with active tuberculosis in the Algerian population of Oran's city.Semantic proximity Read ↗

IFNG +874T/A, IL10 -1082G/A and TNF -308G/A polymorphisms in association with tuberculosis susceptibility: a meta-analysis study.Semantic proximity Read ↗

A single nucleotide polymorphism in the interferon-γ gene (IFNG +874 T/A) is associated with susceptibility to tuberculosisSemantic proximity Read ↗

Cytokine single nucleotide polymorphisms in Iranian patients with pulmonary tuberculosis.Semantic proximity Read ↗

Cytokine gene polymorphisms across tuberculosis clinical spectrum in Pakistani patients.Semantic proximity Read ↗

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