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Article

CIN85 Deficiency Prevents Nephrin Endocytosis and Proteinuria in Diabetes.

Diabetes - 1 Dec 2016

Teng Beina, Schroder Patricia, Müller-Deile Janina, Schenk Heiko, Staggs Lynne, Tossidou Irini, Dikic Ivan, Haller Hermann, Schiffer Mario

Abstract excerpt

Diabetic nephropathy (DN) is the major cause of end-stage renal disease worldwide. Podocytes are important for glomerular filtration barrier function and maintenance of size selectivity in protein filtration in the kidney. Podocyte damage is the basis of many glomerular diseases characterized by loss of interdigitating foot processes and decreased expression of components of the slit diaphragm. Nephrin, a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27531950
DOI: 10.2337/db16-0081
PMCID: PMC5314701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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