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Article

Virulence Gene Regulation by the <i>agr</i> System in <i>Clostridium perfringens</i>

11 Apr 2009

Abstract excerpt

A gram-positive anaerobic pathogen, Clostridium perfringens, causes clostridial myonecrosis or gas gangrene in humans by producing numerous extracellular toxins and enzymes that act in concert to degrade host tissue. The agr system is known to be important for the regulation of virulence genes in a quorum-sensing manner in Staphylococcus aureus. A homologue for S. aureus agrBD (agrBD(Sa)) was identified in the C....

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Identifiers

PMID: 19363118
DOI: 10.1128/jb.01455-08

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