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Effective Natural PCR-RFLP Primer Design for SNP Genotyping Using Teaching-Learning-Based Optimization With Elite Strategy.

IEEE transactions on nanobioscience - 1 Oct 2016

Cheng Yu-Huei, Kuo Che-Nan, Lai Ching-Ming

Abstract excerpt

SNP (single nucleotide polymorphism) genotyping is the determination of genetic variations of SNPs between members of a species. In many laboratories, PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism) is a usually used biotechnology for SNP genotyping, especially in small-scale basic research studies of complex genetic diseases. PCR-RFLP requires an available restriction enzyme at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27529875
DOI: 10.1109/TNB.2016.2597867

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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