Article
Leveraging electronic health records to study pleiotropic effects on bipolar disorder and medical comorbidities.
Translational psychiatry - 16 Aug 2016
Prieto M L, Ryu E, Jenkins G D, Batzler A, Nassan M M, Cuellar-Barboza A B, Pathak J, McElroy S L, Frye M A, Biernacka J M
Abstract excerpt
Patients with bipolar disorder (BD) have a high prevalence of comorbid medical illness. However, the mechanisms underlying these comorbidities with BD are not well known. Certain genetic variants may have pleiotropic effects, increasing the risk of BD and other medical illnesses simultaneously. In this study, we evaluated the association of BD-susceptibility genetic variants with various medical conditions that...
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