Article
The First Pilot Genome-Wide Gene-Environment Study of Depression in the Japanese Population.
PloS one - 1 Jan 2016
Otowa Takeshi, Kawamura Yoshiya, Tsutsumi Akizumi, Kawakami Norito, Kan Chiemi, Shimada Takafumi, Umekage Tadashi, Kasai Kiyoto, Tokunaga Katsushi, Sasaki Tsukasa
Abstract excerpt
Stressful events have been identified as a risk factor for depression. Although gene-environment (G × E) interaction in a limited number of candidate genes has been explored, no genome-wide search has been reported. The aim of the present study is to identify genes that influence the association of stressful events with depression. Therefore, we performed a genome-wide G × E interaction analysis in the Japanese...
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