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Self-administered generational surveys combine with genetic analysis to reveal foundations of depression in Japanese adults.

Journal of affective disorders - 1 Jul 2024

Takano Ryo, Tominaga Yushin, Fu Dong-Jing, Moyer John A, Cheng Yang, Okada Kinya

Abstract excerpt

BACKGROUND: Major depressive disorder is a prevalent psychiatric illness characterized by mood disturbances and influenced by various environmental and genetic factors, yet its etiology remains largely unknown. METHODS: We profiled a self-reported depressive population in Japan with a focus on sociodemographic background, lifestyle, comorbidities, and genetic background, using data from two cohorts, a...

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PMID: 38599254
DOI: 10.1016/j.jad.2024.04.021

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