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Article

Evidence for a Link Between Fkbp5/FKBP5, Early Life Social Relations and Alcohol Drinking in Young Adult Rats and Humans.

Molecular neurobiology - 1 Oct 2017

Nylander Ingrid, Todkar Aniruddha, Granholm Linnea, Vrettou Maria, Bendre Megha, Boon Wout, Andershed Henrik, Tuvblad Catherine, Nilsson Kent W, Comasco Erika

Abstract excerpt

Alcohol misuse has been linked to dysregulation of stress, emotion, and reward brain circuitries. A candidate key mediator of this association is the FK506-binding protein (FKBP5), a negative regulator of the glucocorticoid receptor. The aim of the present study was to further understand the Fkbp5/FKBP5-related genetic underpinnings underlying the relationship between early life social relations and alcohol...

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Source

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Identifiers

PMID: 27709495
DOI: 10.1007/s12035-016-0157-z
PMCID: PMC5583263

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Evidence for a Link Between Fkbp5/FKBP5, Early Life Social Relations and Alcohol Drinking in Young Adult Rats and Humans.PMID 27709495Read ↗

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