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Article

CD4+ T cells with an activated and exhausted phenotype distinguish immunodeficiency during aviremic HIV-2 infection.

AIDS (London, England) - 23 Oct 2016

Buggert Marcus, Frederiksen Juliet, Lund Ole, Betts Michael R, Biague Antonio, Nielsen Morten, Tauriainen Johanna, Norrgren Hans, Medstrand Patrik, Karlsson Annika C, Jansson Marianne

Abstract excerpt

OBJECTIVE: HIV type 2 (HIV-2) represents an attenuated form of HIV, in which many infected individuals remain 'aviremic' without antiretroviral therapy. However, aviremic HIV-2 disease progression exists, and in the current study, we therefore aimed to examine if specific pathological characteristics of CD4 T cells are linked to such outcome. DESIGN: HIV-seronegative (n = 25), HIV type 1 (HIV-1) (n = 33), HIV-2...

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Identifiers

PMID: 27525551
DOI: 10.1097/QAD.0000000000001223
PMCID: PMC5051526

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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