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Article

B-cell subset alterations and correlated factors in HIV-1 infection

23 Jan 2013

Abstract excerpt

OBJECTIVES: During HIV-1 infection, the development, phenotype, and functionality of B cells are impaired. Transitional B cells and aberrant B-cell populations arise in blood, whereas a declined percentage of resting memory B cells is detected. Our study aimed at pinpointing the demographic, immunological, and viral factors driving these pathological findings, and the role of antiretroviral therapy in reverting...

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PMID: 23343911
DOI: 10.1097/qad.0b013e32835edc47

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