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Article

Preliminary Evaluation of the Effect of Investigational Ebola Virus Disease Treatments on Viral Genome Sequences.

The Journal of infectious diseases - 15 Oct 2016

Whitmer Shannon L M, Albariño César, Shepard Samuel S, Dudas Gytis, Sheth Mili, Brown Shelley C, Cannon Deborah, Erickson Bobbie R, Gibbons Aridth, Schuh Amy, Sealy Tara, Ervin Elizabeth, Frace Mike, Uyeki Timothy M, Nichol Stuart T, Ströher Ute

Abstract excerpt

BACKGROUND: Several patients with Ebola virus disease (EVD) managed in the United States have received ZMapp monoclonal antibodies, TKM-Ebola small interfering RNA, brincidofovir, and/or convalescent plasma as investigational therapeutics. METHODS: To investigate whether treatment selected for Ebola virus (EBOV) mutations conferring resistance, viral sequencing was performed on RNA extracted from clinical blood...

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Share to Antibodies, Monoclonal
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ebolavirus

Share to Genome, Viral

Share to Hemorrhagic Fever, Ebola

Share to Molecular Epidemiology

Share to Plasma

Share to RNA, Small Interfering

Source

Identifiers

PMID: 27521366
DOI: 10.1093/infdis/jiw177

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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