Article
Analysis of an Ebola virus disease survivor whose host and viral markers were predictive of death indicates the effectiveness of medical countermeasures and supportive care.
Genome medicine - 11 Jan 2021
Bosworth Andrew, Rickett Natasha Y, Dong Xiaofeng, Ng Lisa F P, García-Dorival Isabel, Matthews David A, Fletcher Tom, Jacobs Michael, Thomson Emma C, Carroll Miles W, Hiscox Julian A
Abstract excerpt
BACKGROUND: Ebola virus disease (EVD) is an often-fatal infection where the effectiveness of medical countermeasures is uncertain. During the West African outbreak (2013-2016), several patients were treated with different types of anti-viral therapies including monoclonal antibody-based cocktails that had the potential to neutralise Ebola virus (EBOV). However, at the time, the efficacy of these therapies was...
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