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Article

Prognosis of Primary Myelofibrosis in the Genomic Era.

Clinical lymphoma, myeloma & leukemia - 1 Aug 2016

Bose Prithviraj, Verstovsek Srdan

Abstract excerpt

Currently, prognostication in primary myelofibrosis (PMF) relies on the International Prognostic Scoring System (IPSS), dynamic IPSS (DIPSS), and DIPSS-plus, which incorporate age, blood counts, constitutional symptoms, circulating blasts, red cell transfusion need, and karyotype. Although the JAK2 V617F mutation was discovered a decade ago and MPL mutations shortly thereafter, it was the recent discovery of CALR...

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Topics

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Share to Cell Transformation, Neoplastic
Share to Epigenesis, Genetic
Share to Gene Expression Profiling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Myeloproliferative Disorders

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Source

Open in PubMed Open full text

Identifiers

PMID: 27521306
DOI: 10.1016/j.clml.2016.02.031
PMCID: PMC4987499

Genes

CALR
JAK2
MPL
ASXL1
SRSF2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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