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Article

Association of IL-1β +3953 C and HLA-DRB1*15 with Coronary Artery and Rheumatic Heart Diseases in South India.

Human immunology - 1 Dec 2016

Sreekanth M S, Esdan Basha S K, Arun Kumar G, Govindaraju S, Pradeep Nayar N, Pitchappan R M

Abstract excerpt

Among the various candidate genes predisposing for cardiovascular diseases, HLA-DRB1* and IL-1β +3953C/T alleles have been implicated repeatedly. To test these in South India, we carried out a case control study of 323 Coronary Artery Disease (CAD) patients, 56 Rheumatic Heart Disease (RHD) patients and 254 endemic controls. The polymorphisms were studied by PCR - SSP and ARMS-PCR methods and results analyzed for...

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Source

Identifiers

PMID: 27521249
DOI: 10.1016/j.humimm.2016.08.003

Genes

CAD
RHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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