Article
The rs12526453 Polymorphism in an Intron of the PHACTR1 Gene and Its Association with 5-Year Mortality of Patients with Myocardial Infarction.
PloS one - 1 Jan 2015
Szpakowicz Anna, Kiliszek Marek, Pepinski Witold, Waszkiewicz Ewa, Franaszczyk Maria, Skawronska Malgorzata, Ploski Rafal, Niemcunowicz-Janica Anna, Burzynska Beata, Tulacz Dorota, Maciejak Agata, Kaminski Marcin Jakub, Opolski Grzegorz, Musial Wlodzimierz Jerzy, Kaminski Karol Adam
Abstract excerpt
OBJECTIVE: The rs12526453 (C/G) is a single nucleotide polymorphism in an intron of the PHACTR1 gene (phosphatase and actin regulator 1). The C allele is associated with increased risk of coronary artery disease in an unknown mechanism. We investigated its association with long-term overall mortality in patients with ST-elevation myocardial infarction (STEMI) treated invasively. METHODS: Two independent groups of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.