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DNA Clutch Probes for Circulating Tumor DNA Analysis.

Journal of the American Chemical Society - 31 Aug 2016

Das Jagotamoy, Ivanov Ivaylo, Sargent Edward H, Kelley Shana O

Abstract excerpt

Progress toward the development of minimally invasive liquid biopsies of disease is being bolstered by breakthroughs in the analysis of circulating tumor DNA (ctDNA): DNA released from cancer cells into the bloodstream. However, robust, sensitive, and specific methods of detecting this emerging analyte are lacking. ctDNA analysis has unique challenges, since it is imperative to distinguish circulating DNA from...

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PMID: 27513828
DOI: 10.1021/jacs.6b05679

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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