Article
Mitochondrial genome association study with peripheral arterial disease and venous thromboembolism.
Atherosclerosis - 1 Sept 2016
Abrantes Patrícia, Rosa Alexandra, Francisco Vânia, Sousa Inês, Xavier Joana M, Oliveira Sofia A
Abstract excerpt
BACKGROUND AND AIMS: Peripheral arterial disease (PAD) and venous thromboembolism (VTE) are vascular traits sharing common modifiable and non-modifiable risk factors. These vascular pathologies have known nuclear-encoded genetic risk factors and the mitochondrial DNA may account for part of the missing heritability. To determine if PAD and VTE have a dual genetic control (mitochondrial and nuclear), we hereby...
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