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Migrating glioma cells express stem cell markers and give rise to new tumors upon xenografting

10 Aug 2016

Abstract excerpt

Glioblastoma (GBM) is the most frequent and malignant brain tumor with an overall survival of only 14.6 months. Although these tumors are treated with surgery, radiation and chemotherapy, recurrence is inevitable. A critical population of tumor cells in terms of therapy, the so-called cancer stem cells (CSCs), has been identified in gliomas and many other cancers. These tumor cells have a stem cell-like phenotype...

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PMID: 27510953
DOI: 10.1007/s11060-016-2221-y

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