Article
Roles of CYP1A1 and CYP2E1 Gene Polymorphisms in Oral Submucous Fibrosis.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016
Yaming Punyo, Urs Aadithya Basavaraj, Saxena Alpana, Zuberi Mariyam
Abstract excerpt
BACKGROUND: Oral submucous fibrosis (OSF) is a precancerous condition with a 4 to13% malignant transformation rate. Related to the habit of areca nut chewing it is mainly prevalent in Southeast Asian countries where the habit of betel quid chewing is frequently practised. On chewing, alkaloids and polyphenols are released which undergo nitrosation and give rise to Nnitrosamines which are cytotoxic agents. CYP450...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
