Article
Association of CYP1A1, GSTM1, and GSTT1 gene polymorphism with risk of oral submucous fibrosis in a section of North Indian population.
Molecular biology reports - 1 Oct 2012
Ghosh Tanima, Gupta Shalini, Bajpai Prachi, Agarwal Deepti, Agarwal Mohit, Gupta O P, Agrawal Deepa
Abstract excerpt
Genetic alterations in the genes expressing drug metabolizing enzymes can make an individual susceptible to various cancers. This study detects the polymorphisms at CYP1A1, GSTM1, and GSTT1 genes in a section of North Indian population and determines the susceptibility to oral submucous fibrosis (OSF). In this case-control study one hundred and two OSF patients were genotyped to detect the GSTM1, GSTT1, CYP1A1...
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