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Article

Association of XRCC1, XRCC3, and NAT2 polymorphisms with the risk of oral submucous fibrosis among eastern Indian population.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Apr 2012

Mukherjee Sanjit, Bhowmik Aneek Das, Roychoudhury Paromita, Mukhopadhyay Kanchan, Ray Jay Gopal, Chaudhuri Keya

Abstract excerpt

BACKGROUND: Arecanut and smokeless tobacco usage is a major cause for oral submucous fibrosis (OSF) and its subsequent development to oral squamous cell carcinoma in South-east Asian population. Polymorphisms at N-acetyltransferase 2 locus, coding for an enzyme catalyzing acetylation of aromatic amines, might cause DNA adduct formation because of improper acetylation of these polyaromatic hydrocarbons. DNA repair...

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Identifiers

PMID: 22092501
DOI: 10.1111/j.1600-0714.2011.01097.x

Genes

XRCC3
NAT2
XRCC1

Variants

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Association of XRCC1, XRCC3, and NAT2 polymorphisms with the risk of oral submucous fibrosis among eastern Indian population.PMID 22092501Read ↗

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Association of NQO1 C609T (Pro187Ser) with risk of Oral Submucous Fibrosis in Eastern Indian populationSemantic proximity Read ↗

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