Article
Analysis of high-order SNP barcodes in mitochondrial D-loop for chronic dialysis susceptibility.
Journal of biomedical informatics - 1 Oct 2016
Yang Cheng-Hong, Lin Yu-Da, Chuang Li-Yeh, Chang Hsueh-Wei
Abstract excerpt
OBJECTIVES: Positively identifying disease-associated single nucleotide polymorphism (SNP) markers in genome-wide studies entails the complex association analysis of a huge number of SNPs. Such large numbers of SNP barcode (SNP/genotype combinations) continue to pose serious computational challenges, especially for high-dimensional data. METHODS: We propose a novel exploiting SNP barcode method based on...
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