Article
Genetic algorithm-generated SNP barcodes of the mitochondrial D-loop for chronic dialysis susceptibility.
Mitochondrial DNA - 1 Jun 2014
Chen Jin-Bor, Chuang Li-Yeh, Lin Yu-Da, Liou Chia-Wei, Lin Tsu-Kung, Lee Wen-Chin, Cheng Ben-Chung, Chang Hsueh-Wei, Yang Cheng-Hong
Abstract excerpt
BACKGROUND AND AIMS: Single nucleotide polymorphism (SNP) interaction analysis can simultaneously evaluate the complex SNP interactions present in complex diseases. However, it is less commonly applied to evaluate the predisposition of chronic dialysis and its computational analysis remains challenging. In this study, we aimed to improve the analysis of SNP-SNP interactions within the mitochondrial D-loop in...
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