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Article

Increased coagulation activity and genetic polymorphisms in the F5, F10 and EPCR genes are associated with breast cancer: a case-control study.

BMC cancer - 19 Nov 2014

Tinholt Mari, Viken Marte Kathrine, Dahm Anders Erik, Vollan Hans Kristian Moen, Sahlberg Kristine Kleivi, Garred Oystein, Børresen-Dale Anne-Lise, Jacobsen Anne Flem, Kristensen Vessela, Bukholm Ida, Kåresen Rolf, Schlichting Ellen, Skretting Grethe, Lie Benedicte Alexandra, Sandset Per Morten, Iversen Nina

Abstract excerpt

BACKGROUND: The procoagulant state in cancer increases the thrombotic risk, but also supports tumor progression. To investigate the molecular mechanisms controlling cancer and hemostasis, we conducted a case-control study of genotypic and phenotypic variables of the tissue factor (TF) pathway of coagulation in breast cancer. METHODS: 366 breast cancer patients and 307 controls were genotyped for SNPs (n = 41) in...

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Identifiers

PMID: 25407022
DOI: 10.1186/1471-2407-14-845
PMCID: PMC4251949

Genes

APC
TFPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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