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Article

Oxidative stress biomarkers across mood episodes in bipolar disorder: potential roles of TrxR1 and PRDX1.

BMC psychiatry - 18 May 2026

Gökçen Onur, Karataş Kader Semra, Akkuş Merve, Dönmez Feyza, Sezgin Ayşe Koçak, Gündüz Meliha Koldemir, Kaymak Güllü

Abstract excerpt

AIM: Oxidative stress is considered to play a role in the etiopathogenesis of bipolar disorder. This study aimed to compare oxidative stress indicators among bipolar disorder patients in different mood states and healthy controls. METHOD: The sample included 101 bipolar patients (33 euthymic, 36 depressive, and 32 manic) and 29 healthy controls. Total antioxidant status (TAS), total oxidation status (TOS),...

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Identifiers

PMID: 42151992
DOI: 10.1186/s12888-026-08179-7
PMCID: PMC13348687

Genes

PRDX1
GPX3
SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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