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Systemic DNA and RNA damage from oxidation after serotonergic treatment of unipolar depression

16 May 2022

Abstract excerpt

Previous studies have indicated that antidepressants that inhibit the serotonin transporter reduces oxidative stress. DNA and RNA damage from oxidation is involved in aging and a range of age-related pathophysiological processes. Here, we studied the urinary excretion of markers of DNA and RNA damage from oxidation, 8-oxodG and 8-oxoGuo, respectively, in the NeuroPharm cohort of 100 drug-free patients with...

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PMID: 35577781
DOI: 10.1038/s41398-022-01969-z

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