Article
TREM2 p.H157Y Variant and the Risk of Alzheimer's Disease: A Meta-Analysis Involving 14,510 Subjects.
Current neurovascular research - 1 Jan 2016
Jiang Teng, Hou Jian-Kang, Gao Qing, Yu Jin-Tai, Zhou Jun-Shan, Zhao Hong-Dong, Zhang Ying-Dong
Abstract excerpt
We recently revealed that p.H157Y (rs2234255), a rare coding variant of triggering receptor expressed on myeloid cells 2 gene (TREM2), was associated with Alzheimer's disease (AD) susceptibility in Han Chinese. Contrastingly, although p.H157Y was previously identified in both AD cases and controls by several sequencing studies, no association of this variant with disease susceptibility was reported. To gain a...
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