Article
Interleukin-6 gene polymorphisms correlate with the progression of nephropathy in Chinese patients with type 2 diabetes: A prospective cohort study.
Diabetes research and clinical practice - 1 Oct 2016
Chang Wen-Tsan, Huang Meng-Chuan, Chung Hsin-Fang, Chiu Yen-Feng, Chen Pao-Shan, Chen Fang-Pei, Lee Chun-Yi, Shin Shyi-Jang, Hwang Shang-Jyh, Huang Ya-Fang, Hsu Chih-Cheng
Abstract excerpt
AIMS: Interleukin-6 (IL-6), an inflammatory cytokine, is considered a candidate gene possibly involved in susceptibility to nephropathy in diabetes. This study aimed to examine whether IL-6 polymorphisms predict the progression of nephropathy in a prospective Chinese cohort of patients with type 2 diabetes. METHODS: A total of 568 type 2 diabetic patients with normoalbuminuria at baseline were followed up for a...
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