Article
The association of the 174G>C polymorphism of interleukin 6 gene with diabetic nephropathy in patients with type 2 diabetes mellitus.
Journal of diabetes and its complications - 1 Jan 2000
Papaoikonomou Stavroula, Tentolouris Nicholas, Tousoulis Dimitris, Papadodiannis Dimitris, Miliou Antigoni, Papageorgiou Nikolaos, Hatzis George, Stefanadis Christodoulos
Abstract excerpt
AIMS: To evaluate the association of 174G>C polymorphism on interleukin-6 (IL-6) gene with diabetic nephropathy in patients with type 2 diabetes. METHODS: A total of 393 Greek subjects with type 2 diabetes (mean age 66.5±10.0years, men n=203, women n=190) were examined. Diabetic nephropathy was defined as presence of microalbuminuria and/or proteinuria. The IL-6 174G>C polymorphism was detected by polymerase...
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