Article
Pancreatic cancer susceptibility loci and their role in survival.
PloS one - 1 Jan 2011
Rizzato Cosmeri, Campa Daniele, Giese Nathalia, Werner Jens, Rachakonda P Sivaramakrishna, Kumar Rajiv, Schanné Michaela, Greenhalf William, Costello Eithne, Khaw Kay-Tee, Key Tim J, Siddiq Afshan, Lorenzo-Bermejo Justo, Burwinkel Barbara, Neoptolemos John P, Büchler Markus W, Hoheisel Jörg D, Bauer Andrea, Canzian Federico
Abstract excerpt
Pancreatic cancer has one of the worst mortality rates of all cancers. Little is known about its etiology, particularly regarding inherited risk. The PanScan project, a genome-wide association study, identified several common polymorphisms affecting pancreatic cancer susceptibility. Single nucleotide polymorphisms (SNPs) in ABO, sonic hedgehog (SHH), telomerase reverse transcriptase (TERT), nuclear receptor...
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