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Article

Hydroxylation of diverse flavonoids by CYP450 BM3 variants: biosynthesis of eriodictyol from naringenin in whole cells and its biological activities.

Microbial cell factories - 5 Aug 2016

Chu Luan Luong, Pandey Ramesh Prasad, Jung Narae, Jung Hye Jin, Kim Eun-Hee, Sohng Jae Kyung

Abstract excerpt

BACKGROUND: Cytochrome P450 monooxygenase constitutes a significant group of oxidative enzymes that can introduce an oxygen atom in a high regio- and stereo-selectivity mode. We used the Bacillus megaterium cytochrome P450 BM3 (CYP450 BM3) and its variants namely mutant 13 (M13) and mutant 15 (M15) for the hydroxylation of diverse class of flavonoids. RESULTS: Among 20 flavonoids, maximum seven flavonoids were...

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Identifiers

PMID: 27495155
DOI: 10.1186/s12934-016-0533-4
PMCID: PMC4974697

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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