Article
Identification of genetic variants predictive of early onset pancreatic cancer through a population science analysis of functional genomic datasets.
Oncotarget - 30 Aug 2016
Chen Jinyun, Wu Xifeng, Huang Yujing, Chen Wei, Brand Randall E, Killary Ann M, Sen Subrata, Frazier Marsha L
Abstract excerpt
Biomarkers are critically needed for the early detection of pancreatic cancer (PC) are urgently needed. Our purpose was to identify a panel of genetic variants that, combined, can predict increased risk for early-onset PC and thereby identify individuals who should begin screening at an early age. Previously, we identified genes using a functional genomic approach that were aberrantly expressed in early pathways...
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