Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic Landscape of Pancreatic Adenocarcinoma in Younger versus Older Patients: Does Age Matter?

8 Jan 2019

Abstract excerpt

PURPOSE: State-of-the-art genomic analyses of pancreatic adenocarcinoma (PDAC) have yielded insight into signaling pathways underlying carcinogenesis. PDAC is characterized by substantial genomic heterogeneity. We aimed to determine whether early-onset PDAC (EOPC; ≤55 years) displays a distinctive molecular landscape from average-age onset PDAC (AOPC; ≥70 years). EXPERIMENTAL DESIGN: Three distinct datasets for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ferroptosis and cancer prognosis
Share to Pancreatic and Hepatic Oncology Research
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30617137
DOI: 10.1158/1078-0432.ccr-18-3042

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic Landscape of Pancreatic Adenocarcinoma in Younger versus Older Patients: Does Age Matter?PMID 30617137Read ↗

Delving into Early-onset Pancreatic Ductal Adenocarcinoma: How Does Age Fit In?Semantic proximity Read ↗

Early-Onset Pancreatic Ductal Adenocarcinoma: Clinical Features, Genomic Landscape, and Treatment-Mediated Survival AdvantageSemantic proximity Read ↗

Pancreatic cancer evolution and heterogeneity: integrating omics and clinical data.Semantic proximity Read ↗

Characterisation of early-onset pancreatic adenocarcinoma molecular profile compared to average-onset pancreatic adenocarcinoma (CARAPAC): A systematic review and a meta-analysis.Semantic proximity Read ↗

Therapeutic trends in pancreatic ductal adenocarcinoma (PDAC)Semantic proximity Read ↗

Clinicopathologic Features and Germline Sequence Variants in Young Patients (≤40 Years Old) With Pancreatic Ductal Adenocarcinoma.Semantic proximity Read ↗

Molecular characteristics of early-onset pancreatic ductal adenocarcinoma.Semantic proximity Read ↗

Next generation sequencing of pancreatic ductal adenocarcinoma: right or wrong?Semantic proximity Read ↗

Cigarette smoking drives earlier development of pancreatic adenocarcinoma among carriers of hereditary pancreatic cancer susceptibility genes.Semantic proximity Read ↗

Multiomic Characterization Reveals a Distinct Molecular Landscape in Young-Onset Pancreatic CancerSemantic proximity Read ↗

Genomic Heterogeneity of Pancreatic Ductal Adenocarcinoma and Its Clinical ImpactSemantic proximity Read ↗

High Prevalence of Hereditary Cancer Syndromes and Outcomes in Adults with Early-Onset Pancreatic CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.