Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A meta‐analysis of reflux genome‐wide association studies in 6750 Northern Europeans from the general population

3 Aug 2016

Abstract excerpt

BACKGROUND: Gastroesophageal reflux disease (GERD), the regurgitation of gastric acids often accompanied by heartburn, affects up to 20% of the general population. Genetic predisposition is suspected from twin and family studies but gene-hunting efforts have so far been scarce and no conclusive genome-wide study has been reported. We exploited data available from general population samples, and studied...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gastroesophageal reflux and treatments
Share to Gastrointestinal motility and disorders
Share to Inflammatory Bowel Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27485664
DOI: 10.1111/nmo.12923

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A meta‐analysis of reflux genome‐wide association studies in 6750 Northern Europeans from the general populationPMID 27485664Read ↗

Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseasesSemantic proximity Read ↗

Unraveling the causality between gastroesophageal reflux disease and increased cancer risk: evidence from the UK Biobank and GWAS consortia.Semantic proximity Read ↗

The role of gene polymorphisms in the occurrence of gastroesophageal reflux disease: A systematic review and meta-analysis of genetic association studies.Semantic proximity Read ↗

Unveiling the genetic overlap and causal links between gastroesophageal reflux disease and asthma.Semantic proximity Read ↗

Systematic analyses of GWAS summary statistics from UK Biobank identified novel susceptibility loci and genes for upper gastrointestinal diseases.Semantic proximity Read ↗

Genetic Association Analysis Between Depression and Gastroesophageal Reflux Disease- Related PhenotypesSemantic proximity Read ↗

Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett’s oesophagus and provides insights into clinical heterogeneity in reflux diagnosisSemantic proximity Read ↗

Causal associations between gastroesophageal reflux disease and gastroduodenal ulcer: A two-sample mendelian randomisation study.Semantic proximity Read ↗

Replication and meta-analyses nominate numerous eosinophilic esophagitis risk genes.Semantic proximity Read ↗

A genome-wide association meta-analysis identifies new eosinophilic esophagitis loci.Semantic proximity Read ↗

Combined GWAS and single cell transcriptomics uncover the underlying genes and cell types in disorders of gut-brain interactionSemantic proximity Read ↗

Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohortsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.