Ultrasound imaging of splenomegaly as a proxy to monitor colon tumor development in Apc(min716/+) mice.

Abstract excerpt

Animal models of colon cancer are widely used to understand the molecular mechanisms and pathogenesis of the disease. These animal models require a substantial investment of time and traditionally necessitate the killing of the animal to measure the tumor progression. Several in vivo imaging techniques are being used in both human clinics and preclinical studies, albeit at high cost and requiring particular...

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