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Telomerase: The Devil Inside

29 Jul 2016

Abstract excerpt

High telomerase activity is detected in nearly all human cancers but most human cells are devoid of telomerase activity. There is well-documented evidence that reactivation of telomerase occurs during cellular transformation. In humans, tumors can rely in reactivation of telomerase or originate in a telomerase positive stem/progenitor cell, or rely in alternative lengthening of telomeres, a telomerase-independent...

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PMID: 27483324
DOI: 10.3390/genes7080043

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