Article
Use of a Multiplex Transcript Method for Analysis of Pseudomonas aeruginosa Gene Expression Profiles in the Cystic Fibrosis Lung.
Infection and immunity - 1 Oct 2016
Gifford Alex H, Willger Sven D, Dolben Emily L, Moulton Lisa A, Dorman Dana B, Bean Heather, Hill Jane E, Hampton Thomas H, Ashare Alix, Hogan Deborah A
Abstract excerpt
The discovery of therapies that modulate Pseudomonas aeruginosa virulence or that can eradicate chronic P. aeruginosa lung infections associated with cystic fibrosis (CF) will be advanced by an improved understanding of P. aeruginosa behavior in vivo We demonstrate the use of multiplexed Nanostring technology to monitor relative abundances of P. aeruginosa transcripts across clinical isolates, in serial samples,...
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