Article
Microarray mRNA expression profiling to study cystic fibrosis.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Ramachandran Shyam, Clarke Luka A, Scheetz Todd E, Amaral Margarida D, McCray Paul B
Abstract excerpt
To understand the links between CFTR mutations and the development of cystic fibrosis (CF) phenotypes, it is imperative to study the transcriptome in affected cell types. Microarray expression profiling provides a platform to study global gene expression in detail. This approach may provide the necessary information to segregate phenotypic characteristics of CF, differentiate between genetic or environmental...
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