Article
Mucoid Pseudomonas aeruginosa isolates maintain the biofilm formation capacity and the gene expression profiles during the chronic lung infection of CF patients.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Apr 2011
Lee Baoleri, Schjerling Charlotte K, Kirkby Nikolai, Hoffmann Nadine, Borup Rehannah, Molin Søren, Høiby Niels, Ciofu Oana
Abstract excerpt
Phenotypic and genotypic diversifications of Pseudomonas aeruginosa in the airways of patients with cystic fibrosis (CF) promote long-term survival of bacteria during chronic lung infection. Twelve clonally related, sequential mucoid and non-mucoid paired P. aeruginosa isolates obtained from three Danish CF patients were investigated. The in vitro biofilm formation capacity was studied under static and flow...
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