Article
Modulation of gene expression by Pseudomonas aeruginosa during chronic infection in the adult cystic fibrosis lung
7 Sept 2013
Abstract excerpt
Chronic Pseudomonas aeruginosa infection is the leading cause of morbidity and mortality in cystic fibrosis (CF) patients. P. aeruginosa isolates undergo significant transcriptomic and proteomic modulation as they adapt to the niche environment of the CF lung and the host defences. This study characterized the in vitro virulence of isogenic strain pairs of P. aeruginosa epidemic or frequent clonal complexes...
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