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Article

Transcriptional Response of Mucoid Pseudomonas aeruginosa to Human Respiratory Mucus

11 Nov 2012

Abstract excerpt

UNLABELLED: Adaptation of bacterial pathogens to a host can lead to the selection and accumulation of specific mutations in their genomes with profound effects on the overall physiology and virulence of the organisms. The opportunistic pathogen Pseudomonas aeruginosa is capable of colonizing the respiratory tract of individuals with cystic fibrosis (CF), where it undergoes evolution to optimize survival as a...

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PMID: 23143799
DOI: 10.1128/mbio.00410-12

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