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Article

Low-frequency nonsynonymous variants in FKBPL and ARPC1B genes are associated with breast cancer risk in Chinese women.

Molecular carcinogenesis - 1 Feb 2017

Zhou Wen, Jiang Yue, Zhu Meng, Hang Dong, Chen Jiaping, Zhou Jing, Dai Juncheng, Ma Hongxia, Hu Zhibin, Jin Guangfu, Sha Jiahao, Shen Hongbing

Abstract excerpt

Genome-wide association studies have reported more than 100 independent common loci associated with breast cancer risk. The contribution of low-frequency or rare variants to breast cancer susceptibility has not been well explored. Thus, we applied exome chip to genotype >200 000 low-frequency and rare variants in 1064 breast cancer cases and 1125 cancer-free controls and subsequently validated promising...

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Identifiers

PMID: 27479355
DOI: 10.1002/mc.22534

Genes

FKBPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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